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24 High CBD Strains: Which is Best for Anxiety and Depression

high CBD strains

High CBD strains do not have that psychoactive property created by high THC strains, but they have therapeutic effects. They work best to manage anxiety and depression. To put it forth, CBD is a non-psychoactive component of the cannabis plant that relieves a patient from diseases and unease, be it anxiety, depression, pain, or swelling. The catch is that high strains of CBD should increase the concentration while bringing the level of THC down as low as possible.

You can get your desired CBD product at well-known CBD store. As you know CBD with unique properties and benefits, high CBD products eliminate anxiety and depression symptoms significantly, which makes them the perfect option to go for.

Whether you are already aware of CBD’s benefits or are a first-time user, this blog will give valuable insights regarding CBD strains and help you maintain your mental well-being.

What Is a High CBD Percentage?

A high CBD percentage means that there is an increased cannabidiol content in a cannabis strain. Usually, any strains that have over 10% CBD are considered high. They produce effective therapeutic effects, including anxiety and pain relief, without being psychoactive. However, some good high CBD strains may peak at over 20% content in their concentration with super-strong medicinal benefits.

Top 24 High CBD Strains Best for Healing

Based on the benefits and their effectiveness, we are listing down 24 high CBD stains that are considered best to cure patients with anxiety, depression, insomnia, and appetite issues.


It is a high-CBD strain that represents an average ratio of 20:1 CBD to THC. This makes it very powerful for therapies and not too psychoactive. It is used to treat anxiety, pain relief, and inflammation and provide a person with a calming and clear-headed feeling.


Harle-Tsu crosses Harlequin and Sour Tsunami with a 20:1 CBD to THC ratio. This strain offers non-intoxicating, mellow effects with significant anti-inflammatory and pain relief properties, best for the treatment of anxiety, stress, and chronic pain.

Tatanka Pure CBD

Tatanka Pure CBD is known for its characteristic high CBD content, which is up to 14% CBD, whereas THC is very low. Its origin was named after the Native American healer. This plant helps smokers stay cool and reduce their anxiety without unwanted psychoactive effects.


This cannabis is derived from Harlequin and Jack the Ripper. It has a mix of both healing properties and psychoactive effects. With a 1:1 ratio of CBD to THC, it is therapeutic in nature, lessens anxiety, and eases pain, with mild psychoactive effects.


Lifter produces the desired energizing effects. The weed strains for anxiety fight off anxiety and depression and provide a clear-headed and focused experience. With 16 – 20% CBD and less than 0.3% THC, it is a perfect option for every day.

CBD Queen

With a high CBD content, CBD Queen has a balanced effect with low contents of THC. Known for its anti-inflammatory properties, this strain is suitable for those with the need for the cure of chronic pain, anxiety, and tension without too much of the psychoactive effect.

CBD Blueberry

CBD Blueberry has a high concentration of CBD that brings out the best of blueberry’s soothing properties. With relaxation and mood lightening at its core, it is perfect for reducing anxiety and stress relief. It is full of flavor with little to no psychoactive properties.


Elektra is another high CBD strain that contains up to 16% CBD and 0.3% THC. This strain contains soothing properties, which make it perfect for treating anxiety, depression, and chronic pain with hardly any psychoactive influence.


Cannatonic is one of the popular high-CBD varieties, with a CBD: THC ratio of about 1:1 and up to 2:1. This blend or combination works best in anxiety, stress, and pain relief and is best known for its relaxing and soothing effect.


Harlequin has high CBD low THC strains with a 5:2 CBD: THC ratio. It reduces and subsides anxiety and stress and does well in times when you need to be up and active during the day. Its well-balanced effects provide a subtle mood lift of your mood with a significant psychoactive effect.

CBD Haze

This variation of strain has a high CBD content. It is known to be uplifting and has anxiety-relieving effects. Due to this, it is mostly used during the day as it keeps the head clear with little psychoactive action. If you have a busy day ahead and you have to stay active, CBD haze is for you.

Purplematic CBD

Purplematic CBD comes with a ratio of 34:1 CBD to THC ratio. This herb is used to have relaxation and calming effects. Therefore, it is appropriate for reducing anxiety and stress with near to no psychoactive activity.


Another cannabinoid similar in its non-psychoactive and non-intoxicating effects is CBG. It has various therapeutic advantages, from anti-inflammatory to antibacterial to many others, and is known as “the mother of all cannabinoids” because it truly works well with other cannabinoids like THC and CBD.

Stephen Hawking

Stephen Hawking Kush has a ratio of 5:1 CBD to THC. This strain is named after the famous physicist and has relaxing and therapeutic effects that treats anxiety, pain very well. Moreover, it gives you a calming feel which is the ultimate need for your well-being.

Critical Mass

Critical mass is another non-intoxicating cannabinoid, which carries a number of therapeutic advantages, such as anti-inflammation and antibacterial properties due to the presence of weed strains for anxiety relief.

Fast Eddy

Fast Eddy is an overall high CBD strain with a 1:1 ratio of CBD to THC. This bud is fast-acting and soft in effect. Mostly, it is used to get rid of anxiety, pain, and stress but without weighing in too heavily with hard-hitting psychoactive impact.

Sour Tsunami

Sour Tsunami is one of the first strains to have a high CBD content. It has a 10:1 ratio for CBD: THC. With a very balanced effect, it performs well in managing anxiety and pain relief, as well as inflammation, without a hard psychoactive effect.

CBD Harlequin

CBD Harlequin works like a standard Harlequin but with a high concentration of CBD. It offers a clear-headed relief over anxiety and stress. If you want to treat your anxiety and distress without strong psychoactive effects, you may use it anytime you want.

CBD Compassion

CBD holds a 1:1 CBD to THC ratio, which makes it one of those strains that provides the best relief. It would be recommended in cases of anxiety, stress, pain relief, or balanced experiences with subtle psychoactive effects.

Royal Highness

Royal Highness has a 1:1 CBD to THC ratio. This strain of CBD for pain elderly people is a treat for those suffering. Its therapeutic properties for anxiety and pain relief offer a little but manageable psychoactive effect that is quite relaxing.


Wine is commonly referred to as cherry wine, an extremely high CBD strain with about a 20:1 CBD: THC ratio. It is an excellent alternative for anxiety and stress that provides users with relaxation and calmness without too much psychoactive effect.

Sweet and Sour Widow

Sweet and Sour Widow has a 1:1 ratio of CBD: THC that most smokers love. This strain has a moderate psychoactive effect, which is used for anxiety, depression, and pain relief and related therapies.

Dance World

Dance World is an industrial hemp strain that is rich in CBD with a 1:1 CBD: THC ratio. It uplifts and energizes the spirit, making a person feel calm and at peace and alleviates feelings of anxiety and depression.


Analgesic refers to pain-relieving properties formed by some substances, including high CBD strains. They are strongly pain-relieving plants for chronic pains without the psychoactive effects that come as a result of high THC strains.

What is the Strongest CBD Strain?

After going through the 24 types of CBD strains, you must be curious about which one is the strongest. So, the strongest CBD strain is referred to as Charlotte’s Web, which is famous for its medicinal purposes since it provides rapid relief in epilepsy, anxiety, and chronic pain. It is highly popular all because of its medical purposes.

What Strain Helps With Anxiety and Depression?

Harlequin is a wonderful strain for dealing with anxiety and depression due to its high CBD content and low THC content. With a 5:2 CBD: THC ratio, it has little to no psychoactive impact and is considered best to manage mental health while maintaining functionality throughout the day.


High CBD low THC strains have a therapeutic impact since they are ideal for seeking relief from anxiety and depression issues. It also cures pain very effectively, which is why it meets the specific requirements and preferences of almost every individual.

Whether you are in need of relief from anxiety or depression or simply seek pain management, these strains will help you get out of the distress and lead a peaceful life. You can visit any credible store to find the best strain for your condition.

However, consulting with a health professional for appropriate dosages and usages related to your situation is a must.

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